Automated Formulation of Materials

HT Formulation and Measurement capability

The Materials Innovation Factory (MIF) has a suite of robotic platforms suitable for automated formulation, and working at a range of scales suitable for materials discovery and product development.

To further advance the MIF capabilities, Royce has invested ~£3M in developing the Formulation Engine (FE) in partnership with Labman Automation, a UK SME focussing on bespoke laboratory automation platforms. The FE is a large modular robotic system that will provide academic and commercial scientists with the tools to increase their scientific outputs quickly and efficiently in a controlled environment.

The FE is designed to be as future-proof as possible and wholly expandable for future research challenges while retaining the benefits of static automation platforms such as high throughput and reliability. With its modular design, it allows up to eight separate independent automated modules to be docked into the main robot platform simultaneously for high throughput and interlinked workflows such as make and measure. Input vials ranging from 2–200ml are easily handled by the FE’s two FANUC arms which deliver materials and consumables to the modules as required so that several workflows can happen independently whilst sharing the robots’ resources.

Dispensing module (DMOD): module dispenses into various consumables fed from the main platform. It dispenses powders into boats in a dehumidified atmosphere. It also contains four fixed syringe needles for low viscosity additions.

Inert processing module (XYZ): gantry robot for moving consumable and performing syringe needle transfers across various consumables from 2ml HPLC vials up to 40ml glass vials. It also houses a Mettler Toledo Quantos for highly accurate powder dispensing. Syringe pumps dispense up to six stock solvents and allow gas caps under nitrogen or a It can cap, crimp, shake and ultrasonicate vials.

Fluid processing module (TOM): providing three independent mixing stages with excellent distributive and dispersive mixing for process-sensitive materials at 50ml or 200ml scale. Gravimetric additions can be made whilst mixing, homogenising and controlling temperature. pH can also be measured and adjusted.

Photocatalysis module (PCAT): completes the photocatalysis workflow for materials discovery and research. Following the XYZ processing module, new catalysts are exposed to light from a solar simulator to promote water splitting and carbon capture. The headspace of each sample is analysed using a mass spectrometer to detect if the reactions were successful.