The Henry Royce Institute
The Henry Royce Institute

Ultra High Performance Liquid Chromatography - Mass Spectrometry System 1 (UPLC -TQD MS)

Waters Acquity UPLC with Waters Xevo TQD

Ultra High Performance Liquid Chromatography System (UPLC) is a technique used to separate, identify, and quantify specific components in mixtures. A triple quadrupole is a mass spectrometer in which the first and third quadrupoles act as mass filters and the second quadrupole fragments the analyte within a collision cell.

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Description

The increased selectivity, improved signal to noise ratio, lower limits of quantitation and wider linear range make this an excellent method for challenging samples. The TQD is connected to a quaternary liquid chromatography system enabling both isocratic and gradient elution.

Specification

  • Waters Xevo TQD

  • Mass Range: 2 to 2048 m/z

  • Scan Speed: Up to 10,000 Da/s

  • Mass Stability: Mass drift < 0.1Da (24h)

  • Up to 16,384 MRM channels

  • ESI, APCI and ESCi® ionization sources

  • Acquisition modes:

  • Full Scan MS

  • Product ion scan

  • Precursor ion scan

  • Multiple reaction monitoring

  • Autosampler: 96 x 2 mL vials

  • Column temperatures: 20 to 65°C

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